PCL Collagen Stimulatore is a biocompatible dermal filler comprising polycaprolactone (PCL) microspheres (suspended in Carboxymethylcellulose CMC gel carrier). It is designed to address signs of facial and skin ageing by providing immediate volume and stimulating the body’s natural production of collagen. This allows for sustained improvements in skin texture and elasticity and natural-looking skin rejuvenation.

There are four main types of PCL Collagen Stimulator, each designed to cater to different aesthetic needs and desired durations of effect. The primary types of PCL Collagen Stimulator fillers are categorised based on their longevity and specific properties, allowing treatments to be tailored to individual patient requirements.
| PCL Collagen Stimulator type | Duration | Suitable for |
| PCL Collagen Stimulator S | ~18 months | Ideal for patients looking for a temporary solution to fine lines and superficial wrinkles. It is suitable for younger patients or those new to dermal fillers who want a less permanent option. |
| PCL Collagen Stimulator M | ~2 years | Suitable for moderate volume loss and deeper wrinkles. It balances longevity and the ability to adjust treatment as needed, making it a popular choice for many patients. |
| PCL Collagen Stimulator L | ~3 years | Ideal for those seeking significant volume restoration and long-lasting results. This type is often recommended for older patients or those with more pronounced signs of ageing. |
| PCL Collagen Stimulator E | ~4 years | Designed for maximum longevity, providing sustained results for patients looking for long-term solutions to facial volume loss and skin laxity. It is ideal for those who prefer fewer treatment sessions over time. |
PCL Collagen Stimulator S and M are approved in Singapore. PCL Collagen Stimulator L and E are not approved in Singapore.
PCL Collagen Stimulator works via a dual-action mechanism. It acts as a scaffold to support the skin, instantly restoring volume and contour. The gel fills in wrinkles and fine lines, providing an immediate cosmetic enhancement.
The true beauty of PCL Collagen Stimulator lies in its ability to stimulate neocollagenesis, which is the process of generating new collagen. As the PCL microspheres are gradually absorbed by the body, they leave behind a framework that encourages collagen synthesis. This process not only enhances skin elasticity and firmness but also improves overall skin quality over time.

PCL Collagen Stimulator is a registered medical device (implant) in Singapore and needs to be injected by a medical professional with advanced postgraduate training. Not every doctor is credentialed to inject PCL Collagen Stimulator- PCL Collagen Stimulator needs to be injected by an aesthetic doctor (with a Certificate of Competency for filler injection), plastic surgeon or dermatologist. Ideally, the doctor should have underwent advanced hands in training in PCL Collagen Stimulator injection and perform a high volume of PCL Collagen Stimulator cases regularly.
PCL Collagen Stimulator is ideal for individuals looking to restore a more youthful appearance by addressing age-related volume loss and skin laxity. The ideal client is someone in the mid 30s to 50s with facial volume loss and early skin laxity, who has tried hyaluronic acid gel dermal fillers before and liked the result and is looking for a longer lasting treatment.
PCL Collagen Stimulator is contraindicated for individuals who are pregnant or who have active facial/ skin infections.
PCL Collagen Stimulator is versatile and can address various cosmetic concerns related to ageing, volume loss, and facial contours. The common facial areas treated with PCL Collagen Stimulator include:

Treatment areas (from top to bottom)- forehead, temples, brows, cheeks, nasolabial folds, chin, jawline
PCL Collagen Stimulator is NOT recommended for the treatment of the: lips, undereye and nose.
This is due to the high risk of nodule formation in these areas.
For the lips and nose- a hyaluronic acid dermal filler is recommended
For the undereye- a purified collagen filler is preferred
Dr Hoe Ying Min believes in providing bespoke and personalised care for each patient. For PCL Collagen Stimulator treatments, injections are delivered with precision using either a fine needle or cannula, ensuring that the product is distributed evenly. This helps to minimise the risk of swelling or complications while providing effective and natural-looking results.
After undergoing PCL Collagen Stimulator treatment, you can expect a combination of immediate and progressive results.
Immediate results include:
Gradual improvements include:

PCL Collagen Stimulator costs $1000-1500 per syringe (1ml), depending on clinic location, doctor’s experience and package. PCL Collagen Stimulator S generally costs $50-100 less than PCL Collagen Stimulator M, which lasts longer
PCL Collagen Stimulator S- $888 nett per syringe
PCL Collagen Stimulator M- $988 nett per syringe
Prices are for first time treatments
PCL Collagen Stimulator is different from other dermal fillers due to its formulation and mechanism of action. Here is a comparison of PCL Collagen Stimulator and other common dermal fillers and collagen stimulators
